"How are you?" is the English phrase that can be used to ask "What's wrong with you?".

This question is often asked as a casual greeting or as a way to check in with someone who appears to be upset or distressed. It is important to note, however, that this question can be sensitive and may be interpreted as intrusive if the person asking is not familiar with the individual or if they are being asked in a public setting.

When asking this question, it is also important to maintain a non-judgmental tone and offer support if the person seems to need it. For example, instead of simply asking "What's wrong?", one could respond with phrases like "I'm sorry to hear that" or "Is there anything I can do to help?".

In summary, "How are you?" is a common English phrase that can be used to ask about someone's well-being when they appear to be upset. However, it is important to use this phrase with sensitivity and offer support if needed.

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